International Journal of Modern Science and Technology · ISSN 2456-0235

Research Article · Medical Sciences · Volume 6, Issue 1 · Jan 2021 · Pages 1–7

The effect of Solvent on the Phytochemical and Antimicrobial activity of Adansonia digitata Leaf

A. A. Alafy, D. Kubmarawa, F. D. Davuram, M. Musa, M. Akwaras

  • A. A. Alafy: Department of Chemistry, School of Physical and Applied Sciences, Modibbo Adama University of, Technology, Yola, Adamawa State, Nigeria.
  • D. Kubmarawa: Department of Chemistry, School of Physical and Applied Sciences, Modibbo Adama University of, Technology, Yola, Adamawa State, Nigeria.
  • F. D. Davuram: Department of Chemistry, School of Physical and Applied Sciences, Modibbo Adama University of, Technology, Yola, Adamawa State, Nigeria.
  • M. Musa: Department of Biochemistry, Biochemistry Laboratory Unit, Gombe State University, Gombe State, Nigeria.
  • M. Akwaras: Department of Veterinary and Science Laboratory Technology, Federal college of Animal and Health, Production Technology, Vom, Plateau State, Nigeria.

Abstract

Adansonia digitata leaf is widely spread in hot drier region of tropical Africa. It is used mostly in the northern part of Nigeria as soup and to treat fatigue, dysentery, disease of urinary tract, snake bite etc. The effect of solvent on the Phytochemical and antimicrobial activity of A. digitata was carefully examined in this research work using ethanol, n-Hexane, ethyl-acetate and Aqueous as extracting solvent, using standard methods. The Phytochemical screening shows the presence of almost all the secondary metabolite tested for such as Glycoside, Saponins, Phytosterols, Phenols, Anthraquinones, Carbohydrate and Tannins in all the four crude extract, Alkaloids, Flavonoids were absent in Aqueous extract and Steroid was also found absent in n-Hexane extract. The antimicrobial activity of the plant ethanol, n-Hexane, ethyl-acetate and Aqueous crude extract was carried out using agar well diffusion method against Escherichia coli, Shigella dysenteriae, Salmonella typhi, Klebsiella pneumoniae, Helicobacter pylori, Pseudomonas aeruginosa, Streptococcus aureus and were all found to be reasonably active and effective against the tested isolates, however ethanol is a better extracting medium for the Phytochemical and antimicrobial activity of A. digitata L than the rest of the solvent used as this gives credence to the used of A. digitata as food and for medicinal purposes.

Keywords

Adansonia digitata; Antimicrobial activity; Phytochemical; Microorganism

References

  1. Alafy AA, Davuram FD, Kubmarawa D, Okechukwu JO, Emmanuel I V. Chemical Composition of Crude Extract and Essential oils Isolated from Baobab Plant Adansonia digitata. International Journal of Modern Science an d Technology 2020;5(7):191-5.
  2. Food and Agriculture Organization. Trade in medicinal plants. In: Economic and Social Department, Food and Agriculture Organization of the United Nations, Rome. 2004;2-3.
  3. Gebauer J, El -Siddig K, Ebert G. Baobab (Adansonia dig itata L.): A review on a multipurpose tree with promising future in the Sudan. Gartenbauwissenschaft. 2002; 67: 155-160.
  4. Dan S, Dan S S. Phytochemical Study of Adansonia. A text of higher learning. Donal Publisher 2nd Edition, page 174. (Adansonia digitata). Feedipedia.org. 1986;8:59.
  5. Barminas JT, Charles M, Emmanuel D. Mineral composition of non -conventional leafy vegetables. Plant Foods for Human Nutrition 1998;53:29-36.
  6. Vertuani S, Braccioli E, Buzzoni V, Manfredini S. Antioxidant capacity of Adansonia digitata fruitpulp and leaves. Acta Phytotherapeutica. 2002;2(6):2-7.
  7. Kubmarawa D, Ajoku GA, Enwerem NM, Okorie DA. Preliminary phytochemical and antimicrobial screening of 50 medicinal plants from Nigeria. Afr J Biotechnol 2007;6:1690-6.
  8. Sofowora AE. M edicinal Plants and Traditional Medicines in Africa. Screening plants for Bioactive agents. 2nd edition. Sunshine house, Ibadan, Nigeria: Spectrum Books Lmt; I badan, Nigeria. 1993;289:134-56.
  9. Harbone JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. Chapman and Hall Ltd. London. 1973;279.
  10. Trease GE, Evans WC. Pharmacognosy. 15th Ed. London: Saunders publishers. 2002.
  11. Mitscher LA, Leu RP,Balhala MS, Beal JI, White R. Antimicrobial agents from higher plants. Introduction, rational a nd methodology, Liayadia 1972;35:157-66.
  12. Ali NA A, Julich WD, Kusnick C, Lindequist U. Screening of Yemeni medicinal plants foranti bacterial and cytotoxicactivities. J Ethnophamacol 2001;74:173-9.
  13. Ogunwade IA. Composition patterns of the essential o ils of the leaves of Eucalyptus, Thuja, Callitris & Melaleuca species growing in Nigeria.PhD.Thesis Department of chemistry university of Nigeria. 2001.
  14. Kubmarawa D Kidah M.I, Shagal M.H. Antimicrobial Activities of Essential oils from some medicinal and Ar omatic plants. British Biotechnology Journal 2016;14(3):1-6.
  15. Zagga AL, Abduljabbar I A, Garko MR. Tsoho B, Gbande S. Phytochemical Composition of Adansonia digi tata Leaf ©2021 The Authors. Published by G. J. Publications under the CC BY license. 7 extracts. Proc eedings o f 6th Biodiversity Conference UniUyo 2018;300-4.
  16. Shagal MH , Kubmarawa D, Alim H. Preliminary phytochemical investigation and antimicrobial evaluation of roots, stem-bark and leaves extracts of Diospyros mespiliformis. International Research Journal of Biochemistry and Bioinformatics 2012;2(1):11-5.
  17. Dahiru D, Malgwi AR, Sambo HS. Growth inhibitory effect of senna siamea leaf extracts on selected microorganisms. American Journal of M edicine and Medical Science 2013;3(5):103-7.